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A Scientific essay in Medical Sciences DOCTORAL THESIS To obtain the degree of doctor from the Radboud University of Nijmegen on the authority of Rector Magnificus, Prof. mr. S.C.J.J. Kortmann, according to the decision of the Council of Deans to be defended in public on Wednesday 30th september, 2009 at 10.30 p.m. By: Miriam Margot Bildt Essen, Germany
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Contents
| Chapter 1 |
General introduction |
| Chapter 2 |
Chemically modified tetracyclines stimulate matrix metalloproteinase-2 production by periodontal ligament cells |
| Chapter 3 |
MMP inhibitors reduce collagen gel contraction and a-smotth muscle actin expression bij PDL cells |
| Chapter 4 |
Callagenolytic fragments and active gelatinase complexes in periodontitis |
| Chapter 5 |
CMT-3 inhibits orthodontic tooth displacement in the rat |
| Chapter 6 | MMPs and TIMPs in crevicular fluid during orthodontic tooth movement |
| Chapter 7 | General discussion |
| Chapter 8 |
Summaries in English and Dutch |