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A Scientific essay in Medical Sciences DOCTORAL THESIS To obtain the degree of doctor from the Radboud University of Nijmegen on the authority of Rector Magnificus, Prof. dr. L.M. Bouter, to be defended in public on Wednesday thurstday 27th November, 2008 at 15.45 p.m. By: Sian Djien Tan Utrecht
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Contents
| Chapter 1 |
General introduction |
| Chapter 2 |
Differences in osteocyte density and bone histomorphometry betweenmen and women and between healthy and osteoporotic subjects |
| Chapter 3 |
Fluid shear stress inhibits TNF-a-induced osteocyte apoptosos |
| Chapter 4 |
Inhibition of osteocyte apoptosis by fluid flow is mediated bij nitric oxide |
| Chapter 5 |
Osteocytes subjected to fluid flow inhibit osteoclast formation and bone resorption |
| Chapter 6 |
Orthodontic force stimulates eNOS and iNOS in rat |
| Chapter 7 |
General discussion |